| Item Type | Name |
|
Concept
|
Adenine
|
|
Concept
|
Actins
|
|
Concept
|
Alanine Transaminase
|
|
Concept
|
Albumins
|
|
Concept
|
Amyloid
|
|
Concept
|
Antigen-Antibody Complex
|
|
Concept
|
Amygdala
|
|
Concept
|
Appetite Regulation
|
|
Concept
|
Arcuate Nucleus of Hypothalamus
|
|
Concept
|
Absorption
|
|
Concept
|
Cyclic AMP
|
|
Concept
|
Acyl Coenzyme A
|
|
Concept
|
Adenine Nucleotides
|
|
Concept
|
alpha 1-Antitrypsin
|
|
Concept
|
Biocompatible Materials
|
|
Concept
|
alpha-MSH
|
|
Concept
|
Adenosine Triphosphate
|
|
Concept
|
Adrenocorticotropic Hormone
|
|
Concept
|
Blood Proteins
|
|
Concept
|
Cell Fractionation
|
|
Concept
|
Cell Membrane Permeability
|
|
Concept
|
Androstadienes
|
|
Concept
|
Hypoxia
|
|
Concept
|
Calmodulin
|
|
Concept
|
Chondrosarcoma
|
|
Concept
|
Chromogranins
|
|
Concept
|
Antioxidants
|
|
Concept
|
Analysis of Variance
|
|
Concept
|
Antibodies, Monoclonal
|
|
Concept
|
Arthritis, Rheumatoid
|
|
Concept
|
Appetite
|
|
Concept
|
Arsenicals
|
|
Concept
|
Benzazepines
|
|
Concept
|
Cell Count
|
|
Concept
|
Cell Differentiation
|
|
Concept
|
Cell Nucleus
|
|
Concept
|
Diabetes Mellitus, Experimental
|
|
Concept
|
Autoantibodies
|
|
Concept
|
Bees
|
|
Concept
|
Coleoptera
|
|
Concept
|
Body Weight
|
|
Concept
|
Endoribonucleases
|
|
Concept
|
Cell Membrane
|
|
Concept
|
Cell Division
|
|
Concept
|
Cell Separation
|
|
Concept
|
Botulinum Toxins
|
|
Concept
|
Biological Evolution
|
|
Concept
|
Clone Cells
|
|
Concept
|
Centrifugation, Density Gradient
|
|
Concept
|
Chelating Agents
|
|
Concept
|
Catalase
|
|
Concept
|
Cell Adhesion
|
|
Concept
|
Cell Cycle
|
|
Concept
|
Food Irradiation
|
|
Concept
|
Cell Transformation, Neoplastic
|
|
Concept
|
Chlorophyll
|
|
Concept
|
Cold Temperature
|
|
Concept
|
Guanine Nucleotides
|
|
Concept
|
Cricetulus
|
|
Concept
|
Clathrin
|
|
Concept
|
Collagen
|
|
Concept
|
Diabetes Mellitus, Type 1
|
|
Concept
|
Diabetes Mellitus, Type 2
|
|
Concept
|
Complement C3
|
|
Concept
|
Immunoglobulin M
|
|
Concept
|
DNA-Binding Proteins
|
|
Concept
|
Dexamethasone
|
|
Concept
|
Drug Synergism
|
|
Concept
|
Diazoxide
|
|
Concept
|
Intermediate Filaments
|
|
Concept
|
Endothelium, Vascular
|
|
Concept
|
Cytoskeleton
|
|
Concept
|
Database Management Systems
|
|
Concept
|
Dogs
|
|
Concept
|
Elastin
|
|
Concept
|
Electrophysiology
|
|
Concept
|
Epithelial Cells
|
|
Concept
|
Eye Proteins
|
|
Concept
|
Fertilizers
|
|
Concept
|
Erythropoietin
|
|
Concept
|
Expert Testimony
|
|
Concept
|
Cocaine
|
|
Concept
|
Complement C5
|
|
Concept
|
Cross-Sectional Studies
|
|
Concept
|
Double-Blind Method
|
|
Concept
|
Drosophila melanogaster
|
|
Concept
|
Food Supply
|
|
Concept
|
Ferritins
|
|
Concept
|
Metalloproteins
|
|
Concept
|
Infant, Newborn
|
|
Concept
|
Infant, Premature
|
|
Concept
|
Influenza, Human
|
|
Concept
|
Insulinoma
|
|
Concept
|
Interferons
|
|
Concept
|
Egtazic Acid
|
|
Concept
|
Deoxyguanosine
|
|
Concept
|
Fibroblast Growth Factors
|
|
Concept
|
Neoplasms, Radiation-Induced
|
|
Concept
|
Neurosecretory Systems
|
|
Concept
|
Guanosine Triphosphate
|
|
Concept
|
Obesity
|
|
Concept
|
Oceans and Seas
|
|
Concept
|
Cyclic GMP
|
|
Concept
|
Histocytochemistry
|
|
Concept
|
Oxygen Radioisotopes
|
|
Concept
|
Dose-Response Relationship, Drug
|
|
Concept
|
Lipoproteins
|
|
Concept
|
Insecticides
|
|
Concept
|
Insulin-Like Growth Factor I
|
|
Concept
|
Environmental Monitoring
|
|
Concept
|
Enterovirus Infections
|
|
Concept
|
Flow Cytometry
|
|
Concept
|
Fluorescent Antibody Technique
|
|
Concept
|
Fluorometry
|
|
Concept
|
Image Interpretation, Computer-Assisted
|
|
Concept
|
Inhibins
|
|
Concept
|
Insect Control
|
|
Concept
|
Interleukin-1
|
|
Concept
|
Isoenzymes
|
|
Concept
|
Glipizide
|
|
Concept
|
Glycerophosphates
|
|
Concept
|
Guanylate Cyclase
|
|
Concept
|
Leucine
|
|
Concept
|
Light
|
|
Concept
|
Lipoproteins, LDL
|
|
Concept
|
Macrophages
|
|
Concept
|
Membrane Glycoproteins
|
|
Concept
|
Membrane Proteins
|
|
Concept
|
Metformin
|
|
Concept
|
Leydig Cells
|
|
Concept
|
Gonadotropin-Releasing Hormone
|
|
Concept
|
Hyaluronoglucosaminidase
|
|
Concept
|
Lymphotoxin-alpha
|
|
Concept
|
Actin Cytoskeleton
|
|
Concept
|
Nerve Tissue Proteins
|
|
Concept
|
Potassium Chloride
|
|
Concept
|
Markov Chains
|
|
Concept
|
Pregnancy
|
|
Concept
|
Immunohistochemistry
|
|
Concept
|
Insecticide Resistance
|
|
Concept
|
Organ Size
|
|
Concept
|
Monosaccharide Transport Proteins
|
|
Concept
|
Muscle, Smooth, Vascular
|
|
Concept
|
Glycogen
|
|
Concept
|
Glycolysis
|
|
Concept
|
Oxidative Phosphorylation
|
|
Concept
|
Pancreatic Neoplasms
|
|
Concept
|
Pancreatic Elastase
|
|
Concept
|
Radioligand Assay
|
|
Concept
|
Rats, Inbred SHR
|
|
Concept
|
Receptors, Somatotropin
|
|
Concept
|
Repetitive Sequences, Nucleic Acid
|
|
Concept
|
Mouthwashes
|
|
Concept
|
Melanocyte-Stimulating Hormones
|
|
Concept
|
Cricetinae
|
|
Concept
|
Hot Temperature
|
|
Concept
|
HeLa Cells
|
|
Concept
|
Paraventricular Hypothalamic Nucleus
|
|
Concept
|
Review Literature as Topic
|
|
Concept
|
RNA Precursors
|
|
Concept
|
Ion Channels
|
|
Concept
|
Neutrophils
|
|
Concept
|
Nitric Oxide
|
|
Concept
|
Laminin
|
|
Concept
|
Phosphodiesterase Inhibitors
|
|
Concept
|
Nuclear Reactors
|
|
Concept
|
Oxidation-Reduction
|
|
Concept
|
Ligands
|
|
Concept
|
Lipopolysaccharides
|
|
Concept
|
Cholesterol, HDL
|
|
Concept
|
Luciferases
|
|
Concept
|
Selection, Genetic
|
|
Concept
|
Oximetry
|
|
Concept
|
Pediculus
|
|
Concept
|
Phosphoproteins
|
|
Concept
|
Photochemistry
|
|
Concept
|
Pituitary Gland, Anterior
|
|
Concept
|
Spermine
|
|
Concept
|
Stimulation, Chemical
|
|
Concept
|
Stress, Physiological
|
|
Concept
|
Pharmaceutic Aids
|
|
Concept
|
Phentolamine
|
|
Concept
|
Phenylalanine
|
|
Concept
|
Phosphorylation
|
|
Concept
|
Muscle Proteins
|
|
Concept
|
Neuropeptide Y
|
|
Concept
|
Poisons
|
|
Concept
|
Prealbumin
|
|
Concept
|
Procollagen
|
|
Concept
|
Power Plants
|
|
Concept
|
Prediabetic State
|
|
Concept
|
Proinsulin
|
|
Concept
|
Epoprostenol
|
|
Concept
|
Pituitary Gland
|
|
Concept
|
Pre-Eclampsia
|
|
Concept
|
Protein Precursors
|
|
Concept
|
Protein-Tyrosine Kinases
|
|
Concept
|
Protein Conformation
|
|
Concept
|
Protein Processing, Post-Translational
|
|
Concept
|
Proteoglycans
|
|
Concept
|
Proto-Oncogene Proteins
|
|
Concept
|
Pseudogenes
|
|
Concept
|
Protease Inhibitors
|
|
Concept
|
Proteins
|
|
Concept
|
Foot-and-Mouth Disease
|
|
Concept
|
Transcription Factors
|
|
Concept
|
Glyburide
|
|
Concept
|
Immunoglobulin G
|
|
Concept
|
Regression Analysis
|
|
Concept
|
Rabbits
|
|
Concept
|
Radiometry
|
|
Concept
|
Rats, Zucker
|
|
Concept
|
Receptors, Cell Surface
|
|
Concept
|
Receptor, Insulin
|
|
Concept
|
Repressor Proteins
|
|
Concept
|
Preventive Medicine
|
|
Concept
|
Complement Factor B
|
|
Concept
|
Risk Factors
|
|
Concept
|
Vasoactive Intestinal Peptide
|
|
Concept
|
Pulmonary Circulation
|
|
Concept
|
Schools
|
|
Concept
|
Receptors, Immunologic
|
|
Concept
|
von Willebrand Factor
|
|
Concept
|
Insulin Resistance
|
|
Concept
|
Intestinal Absorption
|
|
Concept
|
Soil Pollutants
|
|
Concept
|
Solutions
|
|
Concept
|
Somatostatin
|
|
Concept
|
ROC Curve
|
|
Concept
|
Potassium Channels
|
|
Concept
|
Cohort Studies
|
|
Concept
|
Genes, ras
|
|
Concept
|
Rats, Inbred WKY
|
|
Concept
|
Receptors, GABA-A
|
|
Concept
|
Receptors, Transferrin
|
|
Concept
|
Regeneration
|
|
Concept
|
Sexual Behavior, Animal
|
|
Concept
|
Polymorphism, Restriction Fragment Length
|
|
Concept
|
RNA Splicing
|
|
Concept
|
Cadherins
|
|
Concept
|
Interleukin-6
|
|
Concept
|
Sodium
|
|
Concept
|
Spermatogonia
|
|
Concept
|
RNA, Transfer
|
|
Concept
|
Sensitivity and Specificity
|
|
Concept
|
Solar Energy
|
|
Concept
|
Spermidine
|
|
Concept
|
Starvation
|
|
Concept
|
Sulfonylurea Compounds
|
|
Concept
|
Technology Assessment, Biomedical
|
|
Concept
|
Thymidine
|
|
Concept
|
Histones
|
|
Concept
|
Hypothalamic Area, Lateral
|
|
Concept
|
Cluster Analysis
|
|
Concept
|
Linear Models
|
|
Concept
|
Tomography, Emission-Computed
|
|
Concept
|
Protein Biosynthesis
|
|
Concept
|
Succinates
|
|
Concept
|
Synapses
|
|
Concept
|
Space-Time Clustering
|
|
Concept
|
Stem Cells
|
|
Concept
|
Tritium
|
|
Concept
|
Interferon Type I
|
|
Concept
|
CHO Cells
|
|
Concept
|
Stroke Volume
|
|
Concept
|
Oxidants
|
|
Concept
|
Tumor Necrosis Factor-alpha
|
|
Concept
|
Uridine Diphosphate
|
|
Concept
|
Hypertrophy, Right Ventricular
|
|
Concept
|
Testis
|
|
Concept
|
2,2'-Dipyridyl
|
|
Concept
|
Calcium Channels
|
|
Concept
|
Islets of Langerhans
|
|
Concept
|
Uric Acid
|
|
Concept
|
Vaccination
|
|
Concept
|
Arsenites
|
|
Concept
|
Lasers
|
|
Concept
|
Liver Neoplasms, Experimental
|
|
Concept
|
Malonyl Coenzyme A
|
|
Concept
|
Tissue Extracts
|
|
Concept
|
Trans-Activators
|
|
Concept
|
Randomized Controlled Trials as Topic
|
|
Concept
|
Risk Assessment
|
|
Concept
|
Retroelements
|
|
Concept
|
Nicotinic Agonists
|
|
Concept
|
Cell Culture Techniques
|
|
Concept
|
Radiopharmaceuticals
|
|
Concept
|
Enteroendocrine Cells
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Caspases
|
|
Concept
|
Tumor Cells, Cultured
|
|
Concept
|
rac1 GTP-Binding Protein
|
|
Concept
|
Mitogen-Activated Protein Kinases
|
|
Concept
|
Protein Subunits
|
|
Concept
|
Transforming Growth Factor beta
|
|
Concept
|
Aspartic Acid Endopeptidases
|
|
Concept
|
Extracellular Matrix Proteins
|
|
Concept
|
NF-kappa B
|
|
Concept
|
Prosencephalon
|
|
Concept
|
HMGA1a Protein
|
|
Concept
|
Up-Regulation
|
|
Concept
|
Antigens, Differentiation, Myelomonocytic
|
|
Concept
|
Prevalence
|
|
Concept
|
Genes, jun
|
|
Concept
|
Antigens, CD
|
|
Concept
|
3T3 Cells
|
|
Concept
|
Measles
|
|
Concept
|
Milk Proteins
|
|
Concept
|
Cysteine Proteinase Inhibitors
|
|
Concept
|
Proto-Oncogene Proteins c-fos
|
|
Concept
|
Rats, Sprague-Dawley
|
|
Concept
|
Rats, Wistar
|
|
Concept
|
Cyclic AMP Response Element-Binding Protein
|
|
Concept
|
Neuropeptides
|
|
Concept
|
Case-Control Studies
|
|
Concept
|
RNA Interference
|
|
Concept
|
Ephrin-A1
|
|
Concept
|
Alternative Splicing
|
|
Concept
|
Sequence Analysis, DNA
|
|
Concept
|
Protein Structure, Tertiary
|
|
Concept
|
Receptor, IGF Type 1
|
|
Concept
|
Paraffin Embedding
|
|
Concept
|
Treatment Outcome
|
|
Concept
|
Mumps
|
|
Concept
|
Peroxidase
|
|
Concept
|
Neoplasm Metastasis
|
|
Concept
|
Amyloid beta-Protein Precursor
|
|
Concept
|
RNA-Binding Proteins
|
|
Concept
|
Immediate-Early Proteins
|
|
Concept
|
Gene Deletion
|
|
Concept
|
MAP Kinase Kinase 1
|
|
Concept
|
MAP Kinase Kinase 2
|
|
Concept
|
Receptors, Cytoplasmic and Nuclear
|
|
Concept
|
Solitary Nucleus
|
|
Concept
|
DNA, Complementary
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Insulin-Like Growth Factor Binding Protein 1
|
|
Concept
|
Oxidative Stress
|
|
Concept
|
Thapsigargin
|
|
Concept
|
ras Proteins
|
|
Concept
|
Qa-SNARE Proteins
|
|
Concept
|
Spodoptera
|
|
Concept
|
Thrombospondin 1
|
|
Concept
|
Neurturin
|
|
Concept
|
beta Catenin
|
|
Concept
|
Integrin beta1
|
|
Concept
|
Vitronectin
|
|
Concept
|
Staurosporine
|
|
Concept
|
Bone Morphogenetic Protein Receptors, Type II
|
|
Concept
|
Nitric Oxide Synthase Type I
|
|
Concept
|
Caspase 3
|
|
Concept
|
Receptor Protein-Tyrosine Kinases
|
|
Concept
|
MAP Kinase Kinase Kinases
|
|
Concept
|
Calcineurin
|
|
Concept
|
Natriuretic Peptide, Brain
|
|
Concept
|
Melanocortins
|
|
Concept
|
Elafin
|
|
Concept
|
Cross-Over Studies
|
|
Concept
|
Pancreas
|
|
Concept
|
src Homology Domains
|
|
Concept
|
Jurkat Cells
|
|
Concept
|
SOXF Transcription Factors
|
|
Concept
|
Gene Knockout Techniques
|
|
Concept
|
Neurotensin
|
|
Concept
|
HMGB Proteins
|
|
Concept
|
Mitochondrial Proteins
|
|
Concept
|
Collagen Type VIII
|
|
Concept
|
Recycling
|
|
Concept
|
Intercellular Signaling Peptides and Proteins
|
|
Concept
|
Dicarboxylic Acid Transporters
|
|
Concept
|
Primary Cell Culture
|
|
Concept
|
Endostatins
|
|
Concept
|
Receptors, G-Protein-Coupled
|
|
Concept
|
Proprotein Convertase 2
|
|
Concept
|
Positron-Emission Tomography
|
|
Concept
|
Green Fluorescent Proteins
|
|
Concept
|
Proteomics
|
|
Concept
|
Mutant Chimeric Proteins
|
|
Concept
|
Collagen Type XVIII
|
|
Concept
|
Receptor, Melanocortin, Type 4
|
|
Concept
|
Scavenger Receptors, Class E
|
|
Concept
|
Protein Kinase C-delta
|
|
Concept
|
Hypoxia-Inducible Factor 1, alpha Subunit
|
|
Concept
|
Proteasome Endopeptidase Complex
|
|
Concept
|
Mitogen-Activated Protein Kinase 3
|
|
Concept
|
Receptors, Calcitonin
|
|
Concept
|
Receptors, Odorant
|
|
Concept
|
Chloride Channels
|
|
Concept
|
Palmitic Acid
|
|
Concept
|
Endothelin-1
|
|
Concept
|
Area Under Curve
|
|
Concept
|
Ribosomal Protein S6 Kinases
|
|
Concept
|
Proto-Oncogene Proteins c-raf
|
|
Concept
|
Luminescence
|
|
Concept
|
SNARE Proteins
|
|
Concept
|
5' Untranslated Regions
|
|
Concept
|
Response Elements
|
|
Concept
|
Cell Cycle Proteins
|
|
Concept
|
Caco-2 Cells
|
|
Concept
|
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
|
|
Concept
|
rab3 GTP-Binding Proteins
|
|
Concept
|
Hydroxymethylglutaryl-CoA Reductase Inhibitors
|
|
Concept
|
Matrix Metalloproteinase 3
|
|
Concept
|
Pyruvic Acid
|
|
Concept
|
Interleukin-1beta
|
|
Concept
|
Leptin
|
|
Concept
|
Nonmuscle Myosin Type IIA
|
|
Concept
|
Platelet Endothelial Cell Adhesion Molecule-1
|
|
Concept
|
Bone Morphogenetic Proteins
|
|
Concept
|
Thrombospondins
|
|
Concept
|
Sirolimus
|
|
Concept
|
Proteome
|
|
Concept
|
I-kappa B Proteins
|
|
Concept
|
rab3A GTP-Binding Protein
|
|
Concept
|
STAT3 Transcription Factor
|
|
Concept
|
Oncogene Protein v-akt
|
|
Concept
|
Type C Phospholipases
|
|
Concept
|
Photosynthesis
|
|
Concept
|
Plastics
|
|
Concept
|
Pneumonia
|
|
Concept
|
Saccharomyces cerevisiae Proteins
|
|
Concept
|
Preoptic Area
|
|
Concept
|
Prognosis
|
|
Concept
|
Population Dynamics
|
|
Concept
|
Precipitin Tests
|
|
Concept
|
Pro-Opiomelanocortin
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Activating Transcription Factor 3
|
|
Concept
|
Protein Kinase C-epsilon
|
|
Concept
|
Protein Kinase C
|
|
Concept
|
Pulmonary Artery
|
|
Concept
|
Rabies
|
|
Concept
|
Recombinant Proteins
|
|
Concept
|
Radioimmunoassay
|
|
Concept
|
Rats, Inbred Strains
|
|
Concept
|
Ribonucleases
|
|
Concept
|
RNA, Double-Stranded
|
|
Concept
|
Severity of Illness Index
|
|
Concept
|
RNA, Messenger
|
|
Concept
|
Lamins
|
|
Concept
|
Satiety Response
|
|
Concept
|
Glycogen Synthase Kinases
|
|
Concept
|
Glycogen Synthase Kinase 3
|
|
Concept
|
Soil
|
|
Concept
|
Receptors, Leptin
|
|
Concept
|
Stochastic Processes
|
|
Concept
|
Sulfonamides
|
|
Concept
|
Biomedical Research
|
|
Concept
|
3T3-L1 Cells
|
|
Concept
|
Bone Morphogenetic Protein 4
|
|
Concept
|
Proprotein Convertase 1
|
|
Concept
|
Furin
|
|
Concept
|
Shc Signaling Adaptor Proteins
|
|
Concept
|
Nuclear Power Plants
|
|
Concept
|
Prolactin-Releasing Hormone
|
|
Concept
|
HEK293 Cells
|
|
Concept
|
Calcitonin Receptor-Like Protein
|
|
Concept
|
Synaptotagmins
|
|
Concept
|
Nuclear Respiratory Factor 1
|
|
Concept
|
Rats
|
|
Concept
|
Kruppel-Like Transcription Factors
|
|
Concept
|
Sterol Regulatory Element Binding Protein 1
|
|
Concept
|
Nitric Oxide Synthase Type II
|
|
Concept
|
TOR Serine-Threonine Kinases
|
|
Concept
|
High-Throughput Nucleotide Sequencing
|
|
Concept
|
Sex Factors
|
|
Concept
|
Spermatocytes
|
|
Concept
|
Streptozocin
|
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
Insulin-Secreting Cells
|
|
Concept
|
Chemokine CXCL10
|
|
Concept
|
Temperature
|
|
Concept
|
Models, Statistical
|
|
Concept
|
Nuclear Matrix
|
|
Concept
|
Down-Regulation
|
|
Concept
|
R-SNARE Proteins
|
|
Concept
|
NFATC Transcription Factors
|
|
Concept
|
Synaptotagmin I
|
|
Concept
|
HSP40 Heat-Shock Proteins
|
|
Concept
|
Vesicle-Associated Membrane Protein 3
|
|
Concept
|
PTEN Phosphohydrolase
|
|
Concept
|
Toll-Like Receptor 4
|
|
Concept
|
Inhibitor of Differentiation Protein 1
|
|
Concept
|
Multivariate Analysis
|
|
Concept
|
Logistic Models
|
|
Concept
|
Survival Analysis
|
|
Concept
|
Transforming Growth Factor alpha
|
|
Concept
|
Cyclins
|
|
Concept
|
Neuroanatomical Tract-Tracing Techniques
|
|
Concept
|
DNA Copy Number Variations
|
|
Concept
|
Thiazoles
|
|
Concept
|
Cell Death
|
|
Concept
|
Transfection
|
|
Concept
|
Transcription Factor RelA
|
|
Concept
|
Bone Morphogenetic Protein Receptors, Type I
|
|
Concept
|
Ventromedial Hypothalamic Nucleus
|
|
Concept
|
Viral Proteins
|
|
Concept
|
Whooping Cough
|
|
Concept
|
Blotting, Northern
|
|
Concept
|
Reproducibility of Results
|
|
Concept
|
HLA-DP alpha-Chains
|
|
Concept
|
Receptors, Laminin
|
|
Concept
|
Single-Strand Specific DNA and RNA Endonucleases
|
|
Concept
|
Receptors, Glucagon
|
|
Concept
|
Anemia, Iron-Deficiency
|
|
Concept
|
Genes, fos
|
|
Concept
|
GTP-Binding Proteins
|
|
Concept
|
NADPH Oxidases
|
|
Concept
|
Interleukin-1 Receptor-Associated Kinases
|
|
Concept
|
Leukocyte Common Antigens
|
|
Concept
|
Cell Dedifferentiation
|
|
Concept
|
Mitogen-Activated Protein Kinase 1
|
|
Concept
|
Calcium-Calmodulin-Dependent Protein Kinases
|
|
Concept
|
Antiporters
|
|
Concept
|
RNA, Complementary
|
|
Concept
|
Receptors, GABA
|
|
Concept
|
Surface Plasmon Resonance
|
|
Concept
|
Pollination
|
|
Concept
|
cdc42 GTP-Binding Protein
|
|
Concept
|
Son of Sevenless Protein, Drosophila
|
|
Concept
|
Antimicrobial Cationic Peptides
|
|
Concept
|
Homeodomain Proteins
|
|
Concept
|
Nitric Oxide Synthase
|
|
Concept
|
Cell Lineage
|
|
Concept
|
Leukocyte Elastase
|
|
Concept
|
Cation Transport Proteins
|
|
Concept
|
Arsenic Poisoning
|
|
Concept
|
Pericytes
|
|
Concept
|
Untranslated Regions
|
|
Concept
|
Monomeric GTP-Binding Proteins
|
|
Concept
|
GTPase-Activating Proteins
|
|
Concept
|
Receptor, EphA2
|
|
Concept
|
Follistatin
|
|
Concept
|
Casein Kinase II
|
|
Concept
|
JNK Mitogen-Activated Protein Kinases
|
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
|
Concept
|
Organic Anion Transporters
|
|
Concept
|
STAT5 Transcription Factor
|
|
Concept
|
GRB2 Adaptor Protein
|
|
Concept
|
Neural Stem Cells
|
|
Concept
|
Basic Helix-Loop-Helix Transcription Factors
|
|
Concept
|
Transcriptome
|
|
Concept
|
Chromogranin A
|
|
Concept
|
Adrenomedullin
|
|
Concept
|
Janus Kinase 2
|
|
Concept
|
Protein Tyrosine Phosphatase, Non-Receptor Type 1
|
|
Concept
|
Genome-Wide Association Study
|
|
Concept
|
AMP-Activated Protein Kinases
|
|
Concept
|
Bone Morphogenetic Protein 6
|
|
Concept
|
Insulin Receptor Substrate Proteins
|
|
Concept
|
Hep G2 Cells
|
|
Concept
|
Pathology, Molecular
|
|
Concept
|
Precision Medicine
|
|
Concept
|
Dynamins
|
|
Concept
|
RNA, Small Interfering
|
|
Concept
|
Transcription Factors, General
|
|
Concept
|
Fluorescence Recovery After Photobleaching
|
|
Concept
|
Ribosomal Protein S6 Kinases, 70-kDa
|
|
Concept
|
Eukaryotic Initiation Factors
|
|
Concept
|
Endothelial Cells
|
|
Concept
|
Cell Line, Tumor
|
|
Concept
|
Pancreas, Exocrine
|
|
Concept
|
Intracellular Signaling Peptides and Proteins
|
|
Concept
|
Cell Size
|
|
Concept
|
Cell Shape
|
|
Concept
|
Dendrimers
|
|
Concept
|
Suppressor of Cytokine Signaling Proteins
|
|
Concept
|
Toll-Like Receptors
|
|
Concept
|
Protein Kinase C-alpha
|
|
Concept
|
ADAM Proteins
|
|
Concept
|
Forkhead Transcription Factors
|
|
Concept
|
Nitric Oxide Synthase Type III
|
|
Concept
|
Kaplan-Meier Estimate
|
|
Concept
|
Apolipoprotein C-III
|
|
Concept
|
Agouti-Related Protein
|
|
Concept
|
rho-Associated Kinases
|
|
Concept
|
National Heart, Lung, and Blood Institute (U.S.)
|
|
Concept
|
Exosomes
|
|
Concept
|
Growth Differentiation Factor 2
|
|
Concept
|
Drug Discovery
|
|
Concept
|
Cyclin D2
|
|
Concept
|
Islet Amyloid Polypeptide
|
|
Concept
|
Antibodies
|
|
Concept
|
Autopsy
|
|
Concept
|
Axons
|
|
Concept
|
Calcium-Binding Proteins
|
|
Concept
|
Carrier Proteins
|
|
Concept
|
Cell Line
|
|
Concept
|
Cell Survival
|
|
Concept
|
Cells, Cultured
|
|
Concept
|
Chromatin
|
|
Concept
|
Cytoskeletal Proteins
|
|
Concept
|
Diabetes Mellitus
|
|
Concept
|
Distemper
|
|
Concept
|
Dorsomedial Hypothalamic Nucleus
|
|
Concept
|
Enhancer Elements, Genetic
|
|
Concept
|
Epidermal Growth Factor
|
|
Concept
|
Fluorescent Dyes
|
|
Concept
|
Follow-Up Studies
|
|
Concept
|
Foxes
|
|
Concept
|
Guanosine Diphosphate
|
|
Concept
|
Hydroxybutyrates
|
|
Concept
|
Hypothalamus
|
|
Concept
|
Immunoglobulins
|
|
Concept
|
Lipoproteins, HDL
|
|
Concept
|
Luminescent Proteins
|
|
Concept
|
Mesocricetus
|
|
Concept
|
Microtomy
|
|
Concept
|
Nicotine
|
|
Concept
|
Nuclear Proteins
|
|
Concept
|
Odontogenesis
|
|
Concept
|
Palmitoyl Coenzyme A
|
|
Concept
|
Lice Infestations
|
|
Concept
|
Phosphates
|
|
Concept
|
Phylogeny
|
|
Concept
|
Prospective Studies
|
|
Concept
|
Protons
|
|
Concept
|
Pulmonary Embolism
|
|
Concept
|
Rats, Mutant Strains
|
|
Concept
|
Recombinant Fusion Proteins
|
|
Concept
|
Retrospective Studies
|
|
Concept
|
Seawater
|
|
Concept
|
Serine Endopeptidases
|
|
Concept
|
Sphingosine
|
|
Concept
|
Subtilisins
|
|
Concept
|
Thorium
|
|
Concept
|
Thymine
|
|
Concept
|
Tolbutamide
|
|
Concept
|
1-Methyl-3-isobutylxanthine
|
|
Concept
|
Integrins
|
|
Concept
|
Tumor Suppressor Protein p53
|
|
Concept
|
Granulocyte-Macrophage Colony-Stimulating Factor
|
|
Concept
|
Cytokines
|
|
Concept
|
Endothelins
|
|
Concept
|
Sequence Analysis, RNA
|
|
Concept
|
Zeolites
|
|
Concept
|
Cyclic AMP-Dependent Protein Kinases
|
|
Concept
|
DNA Primers
|
|
Concept
|
Protein Isoforms
|
|
Concept
|
3-Hydroxybutyric Acid
|
|
Concept
|
Polymorphism, Single Nucleotide
|
|
Concept
|
ADP-Ribosylation Factors
|
|
Concept
|
Calcium Channels, L-Type
|
|
Concept
|
Quantitative Structure-Activity Relationship
|
|
Concept
|
Collagen Type IV
|
|
Concept
|
Membrane Transport Proteins
|
|
Concept
|
Activins
|
|
Concept
|
Vesicular Transport Proteins
|
|
Concept
|
Adaptor Proteins, Vesicular Transport
|
|
Concept
|
MicroRNAs
|
|
Concept
|
Angiopoietins
|
|
Concept
|
Protein Kinase Inhibitors
|
|
Concept
|
Peroxisome Proliferator-Activated Receptors
|
|
Concept
|
p38 Mitogen-Activated Protein Kinases
|
|
Concept
|
Proto-Oncogene Proteins c-akt
|
|
Concept
|
Glucose Transporter Type 4
|
|
Concept
|
Aquaporin 1
|
|
Concept
|
Bone Morphogenetic Protein Receptors
|
|
Concept
|
Caspase 9
|
|
Concept
|
Glucagon-Like Peptide 2
|
|
Concept
|
Receptor-Like Protein Tyrosine Phosphatases, Class 8
|
|
Concept
|
Ubiquitination
|
|
Concept
|
Infusions, Subcutaneous
|
|
Concept
|
Growth Differentiation Factors
|
|
Concept
|
Growth Differentiation Factor 15
|
|
Concept
|
Research Report
|
|
Concept
|
Microbial Consortia
|
|
Concept
|
HLA-DP beta-Chains
|
|
Concept
|
alpha-2-HS-Glycoprotein
|
|
Academic Article
|
Glucose-regulated translational control of proinsulin biosynthesis with that of the proinsulin endopeptidases PC2 and PC3 in the insulin-producing MIN6 cell line.
|
|
Academic Article
|
Processing of proopiomelanocortin by insulin secretory granule proinsulin processing endopeptidases.
|
|
Academic Article
|
A novel regulatory mechanism for trimeric GTP-binding proteins in the membrane and secretory granule fractions of human and rodent beta cells.
|
|
Academic Article
|
Specific co-ordinated regulation of PC3 and PC2 gene expression with that of preproinsulin in insulin-producing beta TC3 cells.
|
|
Academic Article
|
Insulin-stimulated translocation of GLUT4 glucose transporters requires SNARE-complex proteins.
|
|
Academic Article
|
Insulin-secreting non-islet cells are resistant to autoimmune destruction.
|
|
Academic Article
|
The ratio of mouse insulin I:insulin II does not reflect that of the corresponding preproinsulin mRNAs.
|
|
Academic Article
|
Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo : a specific vascular action of insulin.
|
|
Academic Article
|
Acute stimulation with long chain acyl-CoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI beta-cells).
|
|
Academic Article
|
Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation.
|
|
Academic Article
|
A specific increased expression of insulin receptor substrate 2 in pancreatic beta-cell lines is involved in mediating serum-stimulated beta-cell growth.
|
|
Academic Article
|
Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1).
|
|
Academic Article
|
Synaptotagmin III isoform is compartmentalized in pancreatic beta-cells and has a functional role in exocytosis.
|
|
Academic Article
|
Glycerol-stimulated proinsulin biosynthesis in isolated pancreatic rat islets via adenoviral-induced expression of glycerol kinase is mediated via mitochondrial metabolism.
|
|
Academic Article
|
Cysteine string protein (CSP) is an insulin secretory granule-associated protein regulating beta-cell exocytosis.
|
|
Academic Article
|
Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation.
|
|
Academic Article
|
A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties.
|
|
Academic Article
|
Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells.
|
|
Academic Article
|
Changes in cytoplasmic ATP concentration parallels changes in ATP-regulated K+-channel activity in insulin-secreting cells.
|
|
Academic Article
|
Succinate is a preferential metabolic stimulus-coupling signal for glucose-induced proinsulin biosynthesis translation.
|
|
Academic Article
|
Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling.
|
|
Academic Article
|
Pancreatic beta-cell growth and survival--a role in obesity-linked type 2 diabetes?
|
|
Academic Article
|
Induction of endothelin-1 expression by glucose: an effect of protein kinase C activation.
|
|
Academic Article
|
A low-affinity Ca2+-dependent association of calmodulin with the Rab3A effector domain inversely correlates with insulin exocytosis.
|
|
Academic Article
|
Gene and cell-replacement therapy in the treatment of type 1 diabetes: how high must the standards be set?
|
|
Academic Article
|
Arcuate nucleus-specific leptin receptor gene therapy attenuates the obesity phenotype of Koletsky (fa(k)/fa(k)) rats.
|
|
Academic Article
|
Ca2+-dependent dephosphorylation of kinesin heavy chain on beta-granules in pancreatic beta-cells. Implications for regulated beta-granule transport and insulin exocytosis.
|
|
Academic Article
|
Fatty acid and phorbol ester-mediated interference of mitogenic signaling via novel protein kinase C isoforms in pancreatic beta-cells (INS-1).
|
|
Academic Article
|
Signal transducer and activator of transcription 5 activation is sufficient to drive transcriptional induction of cyclin D2 gene and proliferation of rat pancreatic beta-cells.
|
|
Academic Article
|
Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kappa B in endothelial cells.
|
|
Academic Article
|
Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide.
|
|
Academic Article
|
Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin.
|
|
Academic Article
|
Syncollin inhibits regulated corticotropin secretion from AtT-20 cells through a reduction in the secretory vesicle population.
|
|
Academic Article
|
A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli.
|
|
Academic Article
|
Insulin receptor substrate-2 proteasomal degradation mediated by a mammalian target of rapamycin (mTOR)-induced negative feedback down-regulates protein kinase B-mediated signaling pathway in beta-cells.
|
|
Academic Article
|
Fluorescent cargo proteins in pancreatic beta-cells: design determines secretion kinetics at exocytosis.
|
|
Academic Article
|
Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells.
|
|
Academic Article
|
Insulin receptor substrate 2 plays diverse cell-specific roles in the regulation of glucose transport.
|
|
Academic Article
|
Glucagon-like peptide-1 protects beta cells from cytokine-induced apoptosis and necrosis: role of protein kinase B.
|
|
Academic Article
|
Type 2 diabetes-a matter of beta-cell life and death?
|
|
Academic Article
|
Actin and non-muscle myosin II facilitate apical exocytosis of tear proteins in rabbit lacrimal acinar epithelial cells.
|
|
Academic Article
|
10th EASD/JDRF Oxford Workshop. What is a beta-cell and can we improve it?
|
|
Academic Article
|
Specific regulation of IRS-2 expression by glucose in rat primary pancreatic islet beta-cells.
|
|
Academic Article
|
Insulin action in the brain contributes to glucose lowering during insulin treatment of diabetes.
|
|
Academic Article
|
Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation.
|
|
Academic Article
|
Impact of defined matrix interactions on insulin production by cultured human beta-cells: effect on insulin content, secretion, and gene transcription.
|
|
Academic Article
|
Inositol (1,4,5)-trisphosphate dynamics and intracellular calcium oscillations in pancreatic beta-cells.
|
|
Academic Article
|
Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons.
|
|
Academic Article
|
Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: a role for protein kinase B in the Akt?
|
|
Academic Article
|
Decreasing IRS-2 expression in pancreatic beta-cells (INS-1) promotes apoptosis, which can be compensated for by introduction of IRS-4 expression.
|
|
Academic Article
|
Beta-cell regeneration: epithelial mesenchymal transition pre-EMTpted by lineage tracing?
|
|
Academic Article
|
Proinsulin maturation, misfolding, and proteotoxicity.
|
|
Academic Article
|
A cis-element in the 5' untranslated region of the preproinsulin mRNA (ppIGE) is required for glucose regulation of proinsulin translation.
|
|
Academic Article
|
Regulated autophagy controls hormone content in secretory-deficient pancreatic endocrine beta-cells.
|
|
Academic Article
|
Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell.
|
|
Academic Article
|
Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells.
|
|
Academic Article
|
Glycogen synthase kinase-3 regulates IGFBP-1 gene transcription through the thymine-rich insulin response element.
|
|
Academic Article
|
Stimulation by ATP of proinsulin to insulin conversion in isolated rat pancreatic islet secretory granules. Association with the ATP-dependent proton pump.
|
|
Academic Article
|
Proalbumin to albumin conversion by a proinsulin processing endopeptidase of insulin secretory granules.
|
|
Academic Article
|
Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding.
|
|
Academic Article
|
Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells.
|
|
Academic Article
|
Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death.
|
|
Academic Article
|
The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion.
|
|
Academic Article
|
Exendin 4 controls insulin production in rat islet beta cells predominantly by potentiation of glucose-stimulated proinsulin biosynthesis at the translational level.
|
|
Academic Article
|
The inhibition of proinsulin-processing endopeptidase activities by active-site-directed peptides.
|
|
Academic Article
|
Arf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 ß-cells and rat islets.
|
|
Academic Article
|
Regulation of the biosynthesis of insulin-secretory-granule proteins. Co-ordinate translational control is exerted on some, but not all, granule matrix constituents.
|
|
Academic Article
|
The balance between proinsulin biosynthesis and insulin secretion: where can imbalance lead?
|
|
Academic Article
|
Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance.
|
|
Academic Article
|
Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3ß independent of JNK activation.
|
|
Academic Article
|
Protein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells.
|
|
Academic Article
|
Newly synthesized proinsulin/insulin and stored insulin are released from pancreatic B cells predominantly via a regulated, rather than a constitutive, pathway.
|
|
Academic Article
|
AMP-activated protein kinase attenuates nitric oxide-induced beta-cell death.
|
|
Academic Article
|
Glucolipotoxicity age-dependently impairs beta cell function in rats despite a marked increase in beta cell mass.
|
|
Academic Article
|
Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet.
|
|
Academic Article
|
Formation of a human ß-cell population within pancreatic islets is set early in life.
|
|
Academic Article
|
Degradation of islet amyloid polypeptide by neprilysin.
|
|
Academic Article
|
Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic beta cell via two distinct site-specific endopeptidases.
|
|
Academic Article
|
How does type 1 diabetes develop?: the notion of homicide or ß-cell suicide revisited.
|
|
Academic Article
|
2-5A-dependent endoribonuclease activity and effects of A2'p5'A2'p5'A (2-5A core) in mouse pancreatic islets.
|
|
Academic Article
|
FoxO feedback control of basal IRS-2 expression in pancreatic ß-cells is distinct from that in hepatocytes.
|
|
Academic Article
|
A Kex2-related endopeptidase activity present in rat liver specifically processes the insulin proreceptor.
|
|
Academic Article
|
What beta-cell defect could lead to hyperproinsulinemia in NIDDM? Some clues from recent advances made in understanding the proinsulin-processing mechanism.
|
|
Academic Article
|
Increased secretory demand rather than a defect in the proinsulin conversion mechanism causes hyperproinsulinemia in a glucose-infusion rat model of non-insulin-dependent diabetes mellitus.
|
|
Academic Article
|
Co-secretion of carboxypeptidase H and insulin from isolated rat islets of Langerhans.
|
|
Academic Article
|
PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic beta cells.
|
|
Academic Article
|
Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca2+-dependent calcineurin/NFAT signaling in primary pancreatic islet ß-cells.
|
|
Academic Article
|
The intracellular handling of insulin-related peptides in isolated pancreatic islets. Evidence for differential rates of degradation of insulin and C-peptide.
|
|
Academic Article
|
Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1.
|
|
Academic Article
|
Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.
|
|
Academic Article
|
Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1).
|
|
Academic Article
|
Palmitate inhibition of insulin gene expression is mediated at the transcriptional level via ceramide synthesis.
|
|
Academic Article
|
IRS-3 inhibits IRS-2-mediated signaling in pancreatic beta-cells.
|
|
Academic Article
|
Diazoxide attenuates glucose-induced defects in first-phase insulin release and pulsatile insulin secretion in human islets.
|
|
Academic Article
|
Glucagon-like peptide-1 prevents beta cell glucolipotoxicity.
|
|
Academic Article
|
Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion.
|
|
Academic Article
|
The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species.
|
|
Academic Article
|
Intragranular targeting of syncollin, but not a syncollinGFP chimera, inhibits regulated insulin exocytosis in pancreatic beta-cells.
|
|
Academic Article
|
Effect of interferon and double-stranded RNA on B-cell function in mouse islets of Langerhans.
|
|
Academic Article
|
Glycogen synthase kinase 3 beta mediates high glucose-induced ubiquitination and proteasome degradation of insulin receptor substrate 1.
|
|
Academic Article
|
Effects of glucose and D-3-hydroxybutyrate on human pancreatic islet cell function.
|
|
Academic Article
|
Rab3A effector domain peptides induce insulin exocytosis via a specific interaction with a cytosolic protein doublet.
|
|
Academic Article
|
Proinsulin endopeptidase substrate specificities defined by site-directed mutagenesis of proinsulin.
|
|
Academic Article
|
Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways.
|
|
Academic Article
|
IGF-I and GH post-receptor signaling mechanisms for pancreatic beta-cell replication.
|
|
Academic Article
|
Suppressor of cytokine signalling-3 inhibits Tumor necrosis factor-alpha induced apoptosis and signalling in beta cells.
|
|
Academic Article
|
Intracellular signalling. Key enzyme in leptin-induced anorexia.
|
|
Academic Article
|
ß1 integrin is a crucial regulator of pancreatic ß-cell expansion.
|
|
Academic Article
|
Islet autoantigens: structure, function, localization, and regulation.
|
|
Academic Article
|
Direct autocrine action of insulin on ß-cells: does it make physiological sense?
|
|
Academic Article
|
Characterization of the promoter for the rat and human link protein gene.
|
|
Academic Article
|
ß-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.
|
|
Academic Article
|
ß-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.
|
|
Academic Article
|
Developmental expression of the translocator protein 18 kDa (TSPO) in testicular germ cells.
|
|
Academic Article
|
a1-A680T variant in GUCY1A3 as a candidate conferring protection from pulmonary hypertension among Kyrgyz highlanders.
|
|
Academic Article
|
Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension.
|
|
Academic Article
|
Ensuring quality in a computerized database system: a perinatal network.
|
|
Academic Article
|
Monomethylated-adenines potentiate glucose-induced insulin production and secretion via inhibition of phosphodiesterase activity in rat pancreatic islets.
|
|
Academic Article
|
Pancreatic ß-Cell Adaptive Plasticity in Obesity Increases Insulin Production but Adversely Affects Secretory Function.
|
|
Academic Article
|
RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension.
|
|
Academic Article
|
SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed ß cells.
|
|
Academic Article
|
In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target Slug.
|
|
Academic Article
|
Free Fatty Acid-Induced Inhibition of Glucose and Insulin-Like Growth Factor I-Induced Deoxyribonucleic Acid Synthesis in the Pancreatic ß-Cell Line INS-1* * This work was supported by grants from the NIH (GK-55267), the Juvenile Diabetes Foundation International, the German Research Society, and BetaGene, Inc.
|
|
Academic Article
|
Neurturin and a GLP-1 Analogue Act Synergistically to Alleviate Diabetes in Zucker Diabetic Fatty Rats.
|
|
Academic Article
|
Codependence of Bone Morphogenetic Protein Receptor 2 and Transforming Growth Factor-ß in Elastic Fiber Assembly and Its Perturbation in Pulmonary Arterial Hypertension.
|
|
Academic Article
|
Ca(2+)-regulated serine protease associated with the nuclear scaffold.
|
|
Academic Article
|
Dominant-negative PKC-epsilon impairs apical actin remodeling in parallel with inhibition of carbachol-stimulated secretion in rabbit lacrimal acini.
|
|
Academic Article
|
The c-propeptide of type II procollagen binds to the enhancer region of the type II procollagen gene and regulates its transcription.
|
|
Academic Article
|
Epidemiology of communicable disease in small populations.
|
|
Academic Article
|
BMPR-II deficiency elicits pro-proliferative and anti-apoptotic responses through the activation of TGFß-TAK1-MAPK pathways in PAH.
|
|
Academic Article
|
Characterization of a glucocorticoid responsive element and identification of an AT-rich element that regulate the link protein gene.
|
|
Academic Article
|
Leptin action in the forebrain regulates the hindbrain response to satiety signals.
|
|
Academic Article
|
Reduced plasma levels of small HDL particles transporting fibrinolytic proteins in pulmonary arterial hypertension.
|
|
Academic Article
|
An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28.
|
|
Academic Article
|
Unpaired electrons as probes of catalytic systems.
|
|
Academic Article
|
Red cell distribution width outperforms other potential circulating biomarkers in predicting survival in idiopathic pulmonary arterial hypertension.
|
|
Academic Article
|
Spatial organization of EphA2 at the cell-cell interface modulates trans-endocytosis of ephrinA1.
|
|
Academic Article
|
Muonium--the second radioisotope of hydrogen: a remarkable and unique radiotracer in the chemical, materials, biological and environmental sciences.
|
|
Academic Article
|
Transepithelial transport of poly(amidoamine) dendrimers across Caco-2 cell monolayers.
|
|
Academic Article
|
Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes, and mechanistic insights.
|
|
Academic Article
|
"Spin-labelling" with the second hydrogen radioisotope: radicals formed from squalene by muonium addition.
|
|
Academic Article
|
The Fukushima Daiichi nuclear accident.
|
|
Academic Article
|
Therapeutic targets in pulmonary arterial hypertension.
|
|
Academic Article
|
Subcellular resolution mapping of endogenous cytokine secretion by nano-plasmonic-resonator sensor array.
|
|
Academic Article
|
Persistence of Pancreatic Insulin mRNA Expression and Proinsulin Protein in Type 1 Diabetes Pancreata.
|
|
Academic Article
|
Leptin modulates nutrient reward via inhibitory galanin action on orexin neurons.
|
|
Academic Article
|
Role of oxygen radicals in DNA damage and cancer incidence.
|
|
Academic Article
|
Plasma proteome analysis in patients with pulmonary arterial hypertension: an observational cohort study.
|
|
Academic Article
|
Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity.
|
|
Academic Article
|
Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1.
|
|
Academic Article
|
Identification of the Novel Tooth-Specific Transcription Factor AmeloD.
|
|
Academic Article
|
ß-Cell Control of Insulin Production During Starvation-Refeeding in Male Rats.
|
|
Academic Article
|
The oil question: nature and prognosis.
|
|
Academic Article
|
On the critical behaviour of simple epidemics.
|
|
Academic Article
|
PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE.
|
|
Academic Article
|
Plasmonic nanoparticles and solar cells.
|
|
Academic Article
|
Pulmonary hypertension: biomarkers.
|
|
Academic Article
|
Sustainable nanotechnology.
|
|
Academic Article
|
Fossil fuel use is limited by climate, if not by resources, and "peak soil"..
|
|
Academic Article
|
The dynamic plasticity of insulin production in ß-cells.
|
|
Academic Article
|
The enzymology of proinsulin conversion.
|
|
Academic Article
|
miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia.
|
|
Academic Article
|
Association of synovial inflammation and inflammatory mediators with glenohumeral rotator cuff pathology.
|
|
Academic Article
|
Identification of rare sequence variation underlying heritable pulmonary arterial hypertension.
|
|
Academic Article
|
Pancreatic ß-Cell Rest Replenishes Insulin Secretory Capacity and Attenuates Diabetes in an Extreme Model of Obese Type 2 Diabetes.
|
|
Academic Article
|
Inhibition of upper small intestinal mTOR lowers plasma glucose levels by inhibiting glucose production.
|
|
Academic Article
|
Combined loss of GLP-1R and Y2R does not alter progression of high-fat diet-induced obesity or response to RYGB surgery in mice.
|
|
Academic Article
|
Proteomic Analysis of Restored Insulin Production and Trafficking in Obese Diabetic Mouse Pancreatic Islets Following Euglycemia.
|
|
Academic Article
|
Mendelian randomisation analysis of red cell distribution width in pulmonary arterial hypertension.
|
|
Academic Article
|
Endangered elements, critical raw materials and conflict minerals.
|
|
Academic Article
|
Only 12 years left to readjust for the 1.5-degree climate change option - Says International Panel on Climate Change report: Current commentary.
|
|
Academic Article
|
Calcitonin Receptor Neurons in the Mouse Nucleus Tractus Solitarius Control Energy Balance via the Non-aversive Suppression of Feeding.
|
|
Academic Article
|
Targeting Vessel Formation in Pulmonary Arterial Hypertension: Is the Endostatin-Id1-Thrombospondin 1 Pathway a New Hope?
|
|
Academic Article
|
Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension.
|
|
Academic Article
|
Characterization of Signaling Pathways Associated with Pancreatic ß-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice.
|
|
Academic Article
|
A fluorescent timer reporter enables sorting of insulin secretory granules by age.
|
|
Academic Article
|
Characterization of Signaling Pathways Associated with Pancreatic ß-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice.
|
|
Academic Article
|
A genetic map of the mouse dorsal vagal complex and its role in obesity.
|
|
Academic Article
|
NHLBI-CMREF Workshop Report on Pulmonary Vascular Disease Classification: JACC State-of-the-Art Review.
|
|
Academic Article
|
A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach.
|
|
Academic Article
|
Severe Pulmonary Arterial Hypertension Is Characterized by Increased Neutrophil Elastase and Relative Elafin Deficiency.
|
|
Academic Article
|
NMDARs Drive the Expression of Neuropsychiatric Disorder Risk Genes Within GABAergic Interneuron Subtypes in the Juvenile Brain.
|
|
Academic Article
|
Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic ß-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries.
|
|
Academic Article
|
Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood.
|
|
Academic Article
|
Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain.
|
|
Academic Article
|
Calcineurin/NFATc2 and PI3K/AKT signaling maintains ß-cell identity and function during metabolic and inflammatory stress.
|
|
Academic Article
|
PTPN1 Deficiency Modulates BMPR2 Signaling and Induces Endothelial Dysfunction in Pulmonary Arterial Hypertension.
|
|
Academic Article
|
Author Correction: Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood.
|
|
Concept
|
Cell Plasticity
|
|
Concept
|
Glucagon-Like Peptide-1 Receptor
|
|
Concept
|
Glucagon-Like Peptide-2 Receptor
|
|
Concept
|
Clinical Studies as Topic
|
|
Concept
|
Orexins
|
|
Concept
|
Rotator Cuff Injuries
|
|
Concept
|
Forkhead Box Protein O1
|
|
Concept
|
Suppressor of Cytokine Signaling 3 Protein
|
|
Concept
|
Alpha-Ketoglutarate-Dependent Dioxygenase FTO
|
|
Concept
|
ADAM10 Protein
|
|
Concept
|
ADAMTS13 Protein
|
|
Concept
|
Placenta Growth Factor
|
|
Concept
|
Snail Family Transcription Factors
|
|
Concept
|
Uncoupling Protein 1
|
|
Concept
|
Forkhead Box Protein O3
|
|
Concept
|
Src Homology 2 Domain-Containing, Transforming Protein 1
|
|
Concept
|
Proprotein Convertase 9
|
|
Concept
|
Glycogen Synthase Kinase 3 beta
|
|
Concept
|
Soluble Guanylyl Cyclase
|
|
Concept
|
Fibrillin-1
|
|
Concept
|
Serrate-Jagged Proteins
|
|
Concept
|
Jagged-1 Protein
|
|
Concept
|
Circulating MicroRNA
|
|
Concept
|
Whole Genome Sequencing
|
|
Concept
|
Zinc Transporter 8
|
|
Concept
|
Short Stature Homeobox Protein
|
|
Concept
|
Regulatory-Associated Protein of mTOR
|
|
Concept
|
Sf9 Cells
|
|
Concept
|
Arterial Pressure
|
|
Concept
|
Netrins
|
|
Concept
|
RNA, Long Noncoding
|
|
Concept
|
Fukushima Nuclear Accident
|
|
Concept
|
Pediatric Obesity
|
|
Concept
|
Gene Ontology
|
|
Concept
|
Protein Kinase C beta
|
|
Concept
|
3-Phosphoinositide-Dependent Protein Kinases
|
|
Concept
|
Hepcidins
|
|
Concept
|
Electronic Nicotine Delivery Systems
|
|
Grant
|
Mitogenic Signal Transduction in Pancreatic Beta-Cells
|
|
Grant
|
Metabolic Control of Insulin Exocytosis
|
|
Grant
|
Central Control of Pancreatic Islet Function
|
|
Grant
|
Western Region Islet Study Group
|
|
Grant
|
An Interdisciplinary Molecular Metabolism Training Program
|
|
Grant
|
Metabolic Control of Proinsulin Biosynthesis Translation
|
|
Grant
|
Metabolic Control of Proinsulin Biosynthesis Translation
|
|
Academic Article
|
SOX17 Enhancer Variants Disrupt Transcription Factor Binding And Enhancer Inactivity Drives Pulmonary Hypertension.
|
|
Academic Article
|
Blood DNA methylation profiling identifies cathepsin Z dysregulation in pulmonary arterial hypertension.
|
|
Academic Article
|
Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension.
|